How do I stream one thing to our online audience while a completely different program is unfolding in house?

If I stream video to our online audience while inhouse our pastor is ministering to our congregants, the online users will hear his mic overtop of the video.  We need to use the mic inhouse so the audience can hear him but how do I stop our online users from being able to hear him and yet still hear the videos that will be playing for them?

Send your EW output to a program like OBS, XSplit, etc. and send that programs output to your stream. Set up different Scenes (in OBS, not sure what other programs call it) for the different sources. One for EW, one for the videos, etc., then switch to be tween the scenes as necessary. You can setup as many scenes as you find necessary. Each scene can have it's own audio source so they don't overlap. 

One way is to use a professional online video platform (OVP) that allows you to stream on multiple platforms at once. You can use a third-party tool like Switchboard Live to simulcast your content to multiple platforms simultaneously.

Another option is to use PowerPoint Live in Teams or Live Presentations in PowerPoint for the web. bloxd io. Using PowerPoint for Windows, you can broadcast your PowerPoint presentation over the Internet to a remote audience.